46 Antimicrobial Resistance in Staphylococcus aureus Isolates Occurring in a Community in Zaria

Divya ,G.Rajani ,Shilpadas ,MD.Solaiman

» doi: http://https://ijpsl.co.in//.2021.v11.i01.pp01-05

Abstract

Aiming to provide a framework for empirical antimicrobial therapy based on urine samples, this study examined the antimicrobial susceptibility patterns of Staphylococcus aureus isolated from healthy women to 10 routinely used antimicrobial medications. The method included utilizing normal microbiological methods to grow and screen samples taken from healthy women volunteers in Zaria for S. aureus. To find out how resistant the isolates were to antibiotics, the disc diffusion method was used. Out of 150 urine samples, 54 (or 36% of the total) were found to be S. aureus. Of the 54 isolates, 16 (29.6%), 15 (27.8%), and 23 (42.6%) belonged to pregnant women, unmarried women, and married but not pregnant, respectively. In both the married and single groups, the isolates were very sensitive to gentamicin, ofloxacin, pefloxacin, sparfloxacin, and ciprofloxacin. No statistically significant differences were seen between the two groups for any of the antimicrobial medicines that were evaluated (p>0.05). Of the isolates examined, 34 (63% of the total) shown resistance to several medicines, whereas only 6 (11% of the total) were sensitive to all of the antibiotics. Conclusion: This finding highlights the need to take action to decrease the abundance of bacteria and other microbes that are resistant to antibiotics in otherwise healthy populations. The following terms are used to describe this study: antimicrobial medicines, Staphylococcus aureus, healthy women, community-associated, susceptibility.